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1.
Int J Legal Med ; 135(2): 677-685, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33017037

RESUMO

The Bayesian approach is being a fundamental tool in forensic and legal field where inferences and decisions are made. In this study, a full Bayesian calibration model was developed to make probabilistic inferences about age estimation in a reference sample of 891 periapical X-rays of upper and lower canines. These teeth belonged to both deceased and living adult subjects, aged between 20 and 86 years, coming from five different countries (Turkey, Italy, Portugal, Japan and Mexico). For this purpose, the narrowing of pulp chamber due to the apposition of secondary dentine was analysed by means of the pulp/tooth area ratio. To determine the agreement of the method, intra- and inter-observer differences for measuring process were calculated by means of the intraclass correlation coefficient (ICC) analysis. Observer error tests showed excellent agreement between observers and between repeated assessments. According to the results of the ANCOVA, neither nationality nor sex was associated to the secondary dentine apposition while it is associated with individual's age. The results of the present study indicated that the concept of probability is intrinsically linked to the assessment of age in a forensic context, and the Bayesian approach could be considered a robust tool to overtake the bias generated by traditional regression models, thus helping the decision-making process in a legal framework.


Assuntos
Determinação da Idade pelos Dentes/métodos , Dente Canino/diagnóstico por imagem , Polpa Dentária , Dentina Secundária , Tecido Periapical/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Teorema de Bayes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Estatísticos , Probabilidade
2.
Int Endod J ; 54(2): 172-180, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32918280

RESUMO

AIM: To assess and correlate three distinct states of severely painful endodontically derived inflammation with their depiction on periapical radiographs using periapical index (PAI) scores. METHODOLOGY: During a period of 15 months, 368 consecutively enrolled patients with suspected endodontic emergency conditions were examined at the University of Zurich, Center of Dental Medicine. Cases with a severely painful (numeric rating scale, NRS-11 > 6) endodontically involved tooth and a clear pulpal and apical diagnosis (n = 162) were selected (one tooth per patient). Teeth were divided into three groups according to the clinically diagnosed main location of the inflammatory process: level 1: pulp (positive response to cold test), level 2: periodontium (no response to cold without swelling) and level 3: periapical tissues (no response to cold with swelling). Periapical radiographs were obtained using a digital unit and analysed by two calibrated observers. For level 2, which had the highest PAI variance (n = 76), the PAI scores were further scrutinized regarding their dependence on tooth location and the duration of pain. Data were analysed using chi-squared and non-parametric tests, alpha = 0.05. RESULTS: Overall, the PAI scores correlated well with the clinically diagnosed main location of periapical inflammation (Spearman's rho = 0.5131, P < 0.001), with level 1 having the lowest scores by far (P < 0.001) and level 2 having significantly lower scores compared to level 3 (P < 0.05). However, a PAI score of 5 was found in merely 3 teeth within the entire cohort, and 49% of the teeth in the level 2 group had no radiolucency (PAI < 3). Within level 2, the PAI scores were not dependent on tooth location but were substantially (P < 0.001) higher for teeth which had hurt for more than one week, and for root filled teeth. CONCLUSIONS: For the analysed, severely painful endodontically involved teeth, the clinically diagnosed main location of inflammation was reflected by the periapical index. PAI scores were not significantly influenced by anatomical noise, yet in some cases under-estimated the clinical situation.


Assuntos
Periodontite Periapical , Polpa Dentária , Humanos , Periodontite Periapical/diagnóstico por imagem , Tecido Periapical/diagnóstico por imagem , Obturação do Canal Radicular , Tratamento do Canal Radicular
3.
Av. odontoestomatol ; 36(2): 81-88, mayo-ago. 2020. ilus, tab
Artigo em Espanhol | IBECS | ID: ibc-194689

RESUMO

INTRODUCCIÓN: La implantología oral puede constituir una modalidad terapéutica en el tratamiento prostodóncico de los pacientes con compromiso médico. El estudio muestra la evaluación del tratamiento con implantes en pacientes con diabetes comparados con pacientes sin diabetes. MÉTODOS: 48 pacientes edéntulos totales (24 pacientes diabéticos y 24 no diabéticos) fueron tratados con 96 implantes con superficie arenada y grabada Galimplant ® en la mandíbula para su rehabilitación prostodóncica con sobredentaduras mandibulares. 2 implantes fueron insertados en cada paciente. Los implantes fueron cargados funcionalmente tras un periodo de tiempo de 6 semanas con retenedores de fricción. Los hallazgos clínicos (implantológicos y prostodóncicos) se han seguido durante 7 años. RESULTADOS: Los resultados indican una supervivencia de los implantes del 95,8%. Durante el periodo de seguimeinto clínico se perdieron 4 implantes (dos implantes en cada grupo). La pérdida de hueso marginal media fué de 0,7 mm en ambos grupos. El 100% de los pacientes fueron tratados mediante una sobredentadura implantorretenida con anclajes de fricción. En 14 pacientes se realizaron cambios en los componentes plásticos de los ataches. El seguimiento clínico medio fue de 82,5 meses (60-102 meses). CONCLUSIONES: Los resultados del presente estudio indican que el tratamiento con implantes dentales en pacientes diabéticos es una terapéutica exitosa sin diferencias entre los pacientes diabéticos y no diabéticos


INTRODUCTION: Implant dentistry can to constitute a therapeutic modality in the prosthodontic treatment of medically compromised patients. This study reports the evaluation of treatment with implants in patients with diabetes compared with patients without diabetes. METHODS: 48 edentulous patients (24 diabetic patients and 24 non-diabetic patients) were treated with 96 Galimplant ® sand-blasted and acid-etched surface implants for prosthodontic rehabilitation with mandibular overdentures. Two implants were inserted in each patient. Implants were loaded after a healing free-loading period between 6 weeks with locator attaches. Clinical findings (implant and prosthodontics) were followed during at 7 years. RESULTS: Clinical results indicate a survival rate of implants of 95.8% in both groups. Four implant was lost during the follow-up period (two implants in each group). Media marginal bone loss was 0.7 mm in both groups. 100% of patients were treated with overdentures retained with 2 implants with locator attaches. Changes in plastic components of attaches were reported in 14 patients. The media follow-up was of 82.5 months (60-102 months). CONCLUSIONS: Clinical results of this study indicate that treatment with dental implants in diabetic patients is a successful implant treatment without differences with nondiabetic patients


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Implantes Dentários , Arcada Edêntula/cirurgia , Diabetes Mellitus , Revestimento de Dentadura , Prostodontia/métodos , Tomografia Computadorizada por Raios X/métodos , Antibioticoprofilaxia/métodos , Clorexidina/uso terapêutico , Tecido Periapical/diagnóstico por imagem , Tecido Periapical/patologia , Análise de Variância
4.
Av. odontoestomatol ; 36(2): 99-106, mayo-ago. 2020. ilus
Artigo em Espanhol | IBECS | ID: ibc-194691

RESUMO

El uso de pilares de cicatrización transmucosos previos a la colocación del pilar protésico definitivo es una técnica que se ha desarrollado durante muchos años en la implantología clásica. La desconexión y conexión de forma repetida de estos pilares o aditamentos dan lugar a una respuesta ósea negativa que se manifiesta en forma de pérdida de hueso a nivel de la cresta marginal, acompañada por una migración apical de tejidos blandos. Este artículo pretende realizar una revisión de la literatura del estado actual del uso de los pilares transmucosos definitivos con colocación inmediata el día de la inserción de los implantes y el mantenimiento del sellado biológico, minimizando la pérdida ósea periimplantaria y remodelando de forma adecuada los tejidos blandos adyacentes, frente al protocolo tradiciónal del uso de aditamentos que se desconectan en multiples ocasiones produciendo pérdida ósea periimplantaria. La evidencia científica sugiere que los mejores resultados biológicos, estéticos y funciónales se consiguen con el uso del pilar definitivo colocado de forma inmediata a la inserción del implante, especialmente en implantes colocados de forma yuxtacrestal y en implantes postextracción


The use of transmucosal healing abutments before the placement of the definitive prosthetic abutment is a technique that has been developed for many years in classical implantology. Repeated disconnection and connection of theses abutments result in a negative bone response that manifests as bone loss at the marginal ridge level, accompanied by apical soft tissue migration. This article aims to review the current status in the scientific literature of the use of the definitive transepithelial abutments with immediate placement on the day of implant insertion and maintenance of the biological seal, minimizing peri-implant bone loss and adequately remodeling the adjacent soft tissues, compared to the traditional protocol of the use of abutments that are disconnected on multiple occasions producing peri-implant bone loss. Scientific evidence suggests that the best biological, aesthetic, and functional results are achieved with the use of the definitive abutment placed immediately after implant insertion, especially in yuxtacrestal implants and post-extraction implants


Assuntos
Humanos , Projeto do Implante Dentário-Pivô/métodos , Carga Imediata em Implante Dentário/métodos , Implantes Dentários , Dente Suporte , Mucosa Bucal , Tecido Periapical/diagnóstico por imagem , Tecido Periapical/cirurgia
5.
Sci Rep ; 10(1): 12536, 2020 07 27.
Artigo em Inglês | MEDLINE | ID: mdl-32719323

RESUMO

Control of blood clotting in root canal systems is one of the most critical and difficult concerns for regenerative endodontics therapy (RET). The purpose of this study was to investigate the effects of using gelatin- and fibrin-based hemostatic hydrogels as a scaffold on pulp regeneration in a minipig model. Cell viability of human dental pulp stem cells cultured three-dimensionally in gelatin-based and fibrin-based scaffolds was evaluated by MTT and live/dead assay. RET was performed on 24 immature premolars with an autologous blood clot (PC), gelatin-based and fibrin-based hemostatic matrices (GM and FM), or without the insertion of a scaffold (NC). The follow-up period was 12 weeks. Radiographic and histologic assessments for pulp regeneration were performed. Gelatin-based scaffolds exhibited significantly higher cell viability than fibrin-based scaffolds after 15 days (P < 0.05). The PC and GM groups showed favorable root development without inflammation and newly mineralized tissue deposited in the root canal system, while FM group presented inflammatory changes with the continuation of root development. The NC group exhibited internal root resorption with periapical lesions. The application of GM in RET led to favorable clinical outcomes of root development without inflammatory changes compared to conventional RET. Our results suggest that GM may serve as a viable regenerative scaffold for pulp regeneration.


Assuntos
Polpa Dentária/fisiologia , Hemostáticos/farmacologia , Regeneração/efeitos dos fármacos , Tecidos Suporte/química , Dente/fisiologia , Adulto , Animais , Sobrevivência Celular/efeitos dos fármacos , Polpa Dentária/diagnóstico por imagem , Polpa Dentária/efeitos dos fármacos , Fibrina/farmacologia , Gelatina/farmacologia , Humanos , Modelos Animais , Tecido Periapical/diagnóstico por imagem , Tecido Periapical/efeitos dos fármacos , Células-Tronco/citologia , Células-Tronco/efeitos dos fármacos , Suínos , Porco Miniatura , Dente/diagnóstico por imagem , Dente/efeitos dos fármacos , Adulto Jovem
6.
J Appl Oral Sci ; 27: e20180693, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31596370

RESUMO

OBJECTIVES: To compare the sealing ability and biocompatibility of Biodentine with mineral trioxide aggregate (MTA) when used as root-end filling materials. METHODOLOGY: The Cell Counting Kit-8 (CCK-8) assay was used to compare the cytotoxicity of MTA and Biodentine. Twenty-one extracted teeth with a single canal were immersed in an acidic silver nitrate solution after root-end filling. Then, the volume and depth of silver nitrate that infiltrated the apical portion of the teeth were analyzed using micro-computed tomography (micro-CT). Seventy-two roots from 3 female beagle dogs were randomly distributed into 3 groups and apical surgery was performed. After six months, the volume of the bone defect surrounding these roots was analyzed using micro-CT. RESULTS: Based on the results of the CCK-8 assay, MTA and Biodentine did not show statistically significant differences in cytotoxicity (P>0.05). The volume and the depth of the infiltrated nitrate solution were greater in the MTA group than in the Biodentine group (P<0.05). The volume of the bone defect was larger in the MTA group than in the Biodentine group. However, the difference was not significant (P>0.05). The volumes of the bone defects in the MTA and Biodentine groups were smaller than the group without any filling materials (P<0.05). CONCLUSIONS: MTA and Biodentine exhibited comparable cellular biocompatibility. Biodentine showed a superior sealing ability to MTA in root-end filling. Both Biodentine and MTA promoted periradicular bone healing in beagle dog periradicular surgery models.


Assuntos
Compostos de Alumínio/farmacologia , Compostos de Cálcio/farmacologia , Óxidos/farmacologia , Tecido Periapical/efeitos dos fármacos , Ligamento Periodontal/efeitos dos fármacos , Materiais Restauradores do Canal Radicular/farmacologia , Tratamento do Canal Radicular/métodos , Silicatos/farmacologia , Cicatrização/efeitos dos fármacos , Adolescente , Animais , Regeneração Óssea/efeitos dos fármacos , Contagem de Células , Células Cultivadas , Cães , Combinação de Medicamentos , Humanos , Masculino , Teste de Materiais , Osteogênese/efeitos dos fármacos , Tecido Periapical/citologia , Tecido Periapical/diagnóstico por imagem , Ligamento Periodontal/diagnóstico por imagem , Reprodutibilidade dos Testes , Fatores de Tempo , Raiz Dentária/diagnóstico por imagem , Raiz Dentária/efeitos dos fármacos , Raiz Dentária/cirurgia , Resultado do Tratamento , Microtomografia por Raio-X , Adulto Jovem
8.
Rev. bras. ciênc. vet ; 26(3): 69-74, jul./set. 2019. ilus
Artigo em Português | LILACS, VETINDEX | ID: biblio-1491644

RESUMO

A radiografia intra-oral é um método de diagnóstico por imagem essencial em pacientes submetidos a tratamento odontológico de qualquer natureza, especialmente em casos de doença peridontal. Permite a avaliação de estruturas ósseas e dentárias, elucidando múltiplos diagnósticos que não são firmados clinicamente. Inclui-se no estudo radiográfico a análise da integridade da lâmina dura, do ligamento periodontal, de afecções dentárias como abscessos periapicais, cistos, alterações de desenvolvimento coronário e radicular, agenesias, dentes inclusos ou supranumerários, raízes fraturadas remanescentes na região subgengival, reabsorções dentárias ou ósseas (associadas à doença periodontal ou neoplasias) e estruturas internas do dente (diâmetro da câmara pulpar e canal radicular). O presente artigo visa, portanto, mostrar através da apresentação de casos clínicos, a relevância do exame radiográfico para a correta abordagem diagnóstica e terapêutica de afecções subclínicas, mesmo em pacientes sem sinais de dor ou supostamente portadores de apenas gengivite. Foram relatados um caso de hipoplasia radicular, um de cisto de origem dentária e outro de reabsorção dentária, todos diagnosticados após a realização da documentação radiográfica intra-oral.


The intra-oral radiography is an essential diagnosis imaging method, in patients submitted to dental treatment of any nature, especially cases of periodontal diseases. It allows the evaluation of structural bone and dental diseases, elucidating multiple diagnoses, which are not clinically proven. The radiographic study includes the analysis of the periodontal ligament and lamina dura integrity, dental anomalies such as periapical abscesses, cysts, coronary and root development failures, agenesis, unerupted or supernumerary teeth, fractured roots remaining in the subgingival area, tooth or bone resorption, (associated with neoplasia or periodontal disease) and Internal tooth structures such as diameter of pulp chamber and root canal. The present article aims to show, through clinical case reports, the relevance of the radiographic examination towards the correct diagnosis and therapeutic approach of subclinical infections, even in patients without signs of pain or supposedly gingivitis bearers. Amongst the reported cases, there is a root hipoplasia, a dental origin cyst and a tooth resorption, all diagnosed after intra-oral radiographic completion.


Assuntos
Animais , Gatos , Cães , Fotografia Dentária/veterinária , Periodontite Periapical/diagnóstico por imagem , Periodontite Periapical/veterinária , Radiografia Dentária/veterinária , Tecido Periapical/diagnóstico por imagem
9.
Front Immunol ; 10: 307, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30863409

RESUMO

Periapical periodontitis results from pulpal infection leading to pulpal necrosis and resorption of periapical bone. The current treatment is root canal therapy, which attempts to eliminate infection and necrotic tissue. But, in some cases periapical inflammation doesn't resolve even after treatment. Resolvins belongs to a large family of specialized pro-resolving lipid mediators that actively resolves inflammation signaling via specific receptors. Resolvin D2 (RvD2), a metabolite of docosahexaenoic acid (DHA), was tested as an intracanal medicament in rats in vivo. Mechanism was evaluated in rat primary dental pulp cells (DPCs) in vitro. The results demonstrate that RvD2 reduces inflammatory cell infiltrate, periapical lesion size, and fosters pulp like tissue regeneration and healing of periapical lesion. RvD2 enhanced expression of its receptor, GPR18, dentin matrix acidic phosphoprotein 1 (DMP1) and mineralization in vivo and in vitro. Moreover, RvD2 induces phosphorylation of Stat3 transcription factor in dental pulp cells. We conclude that intracanal treatment with RvD2 resolves inflammation and promoting calcification around root apex and healing of periapical bone lesions. The data suggest that RvD2 induces active resolution of inflammation with pulp-like tissue regeneration after root canal infection and thus maybe suitable for treating periapical lesions.


Assuntos
Ácidos Docosa-Hexaenoicos/farmacologia , Inflamação/prevenção & controle , Periodontite Periapical/prevenção & controle , Tecido Periapical/efeitos dos fármacos , Cicatrização/efeitos dos fármacos , Animais , Células Cultivadas , Polpa Dentária/citologia , Polpa Dentária/efeitos dos fármacos , Polpa Dentária/metabolismo , Proteínas da Matriz Extracelular/genética , Proteínas da Matriz Extracelular/metabolismo , Expressão Gênica/efeitos dos fármacos , Masculino , Tecido Periapical/diagnóstico por imagem , Tecido Periapical/patologia , Fosfoproteínas/genética , Fosfoproteínas/metabolismo , Fosforilação/efeitos dos fármacos , Ratos Wistar , Receptores de Canabinoides/genética , Receptores de Canabinoides/metabolismo , Tratamento do Canal Radicular/métodos , Fator de Transcrição STAT3/metabolismo , Microtomografia por Raio-X/métodos
10.
J. appl. oral sci ; 27: e20180693, 2019. graf
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1040226

RESUMO

ABSTRACT Objectives: To compare the sealing ability and biocompatibility of Biodentine with mineral trioxide aggregate (MTA) when used as root-end filling materials. Methodology: The Cell Counting Kit-8 (CCK-8) assay was used to compare the cytotoxicity of MTA and Biodentine. Twenty-one extracted teeth with a single canal were immersed in an acidic silver nitrate solution after root-end filling. Then, the volume and depth of silver nitrate that infiltrated the apical portion of the teeth were analyzed using micro-computed tomography (micro-CT). Seventy-two roots from 3 female beagle dogs were randomly distributed into 3 groups and apical surgery was performed. After six months, the volume of the bone defect surrounding these roots was analyzed using micro-CT. Results: Based on the results of the CCK-8 assay, MTA and Biodentine did not show statistically significant differences in cytotoxicity (P>0.05). The volume and the depth of the infiltrated nitrate solution were greater in the MTA group than in the Biodentine group (P<0.05). The volume of the bone defect was larger in the MTA group than in the Biodentine group. However, the difference was not significant (P>0.05). The volumes of the bone defects in the MTA and Biodentine groups were smaller than the group without any filling materials (P<0.05). Conclusions: MTA and Biodentine exhibited comparable cellular biocompatibility. Biodentine showed a superior sealing ability to MTA in root-end filling. Both Biodentine and MTA promoted periradicular bone healing in beagle dog periradicular surgery models.


Assuntos
Humanos , Animais , Masculino , Adolescente , Cães , Óxidos/farmacologia , Tecido Periapical/efeitos dos fármacos , Ligamento Periodontal/efeitos dos fármacos , Materiais Restauradores do Canal Radicular/farmacologia , Tratamento do Canal Radicular/métodos , Cicatrização/efeitos dos fármacos , Silicatos/farmacologia , Compostos de Cálcio/farmacologia , Compostos de Alumínio/farmacologia , Osteogênese/efeitos dos fármacos , Tecido Periapical/citologia , Tecido Periapical/diagnóstico por imagem , Ligamento Periodontal/diagnóstico por imagem , Fatores de Tempo , Raiz Dentária/cirurgia , Raiz Dentária/efeitos dos fármacos , Raiz Dentária/diagnóstico por imagem , Regeneração Óssea/efeitos dos fármacos , Teste de Materiais , Contagem de Células , Células Cultivadas , Reprodutibilidade dos Testes , Resultado do Tratamento , Combinação de Medicamentos , Microtomografia por Raio-X
11.
Endodoncia (Madr.) ; 36(3): 8-21, dic. 2018. ilus
Artigo em Espanhol | IBECS | ID: ibc-178382

RESUMO

La Tomografía Computarizada de Haz Cónico (TCHC) (Cone Beam Computed Tomography - CBCT) es un método de imagen que nos ofrece en Endodoncia unas ventajas relevantes sobre la radiografía periapical y otras técnicas radiográficas a la hora de establecer un diagnóstico y plan de tratamiento adecuados. Debemos tener en cuenta, no obstante, que no se debe hacer de manera rutinaria y que no todos los aparatos ni todas las modalidades (campo de adquisición y resolución espacial) están indicadas para su uso en el campo de la endodoncia. Debemos tener un conocimiento técnico mínimo de las cualidades físicas de esta tecnología, para poder realizar una adquisición de datos que sea correcta en cuanto a la radiación del paciente (la menor posible), y en cuanto a la resolución espacial (la mayor posible) para la tarea diagnóstica que vamos a realizar. Repasaremos las indicaciones de uso de el CBCT en endodoncia, el porqué de sus indicaciones y casos clínicos que demuestran la relevancia de la utilización de esta tecnología en Endodoncia


No disponible


Assuntos
Humanos , Dente não Vital/diagnóstico por imagem , Tomografia Computadorizada de Feixe Cônico/métodos , Endodontia/métodos , Doenças Periapicais/diagnóstico por imagem , Tecido Periapical/diagnóstico por imagem
12.
Endodoncia (Madr.) ; 36(3): 32-42, dic. 2018. ilus
Artigo em Espanhol | IBECS | ID: ibc-178384

RESUMO

La evaluación radiográfica y las pruebas diagnósticas son de vital importancia para realizar un adecuado plan de tratamiento en endodoncia. En el campo de la endodoncia, tradicionalmente se han utilizado diferentes pruebas como la palpación, la percusión, las pruebas de sensibilidad pulpar y las radiografías periapicales (RP). Hasta la actualidad las RP (convencionales o digitales) han sido un complemento indispensable para realizar el tratamiento endodóntico, así como para determinar el éxito de dicho tratamiento. Sin embargo, está demostrado que las RP presentan ciertas limitaciones como superposiciones de estructuras anatómicas, la visión en dos dimensiones (2D) y la distorsión geométrica. Las imágenes obtenidas mediante RP ofrecen solamente datos de la dimensión mesio-distal, lo que dificulta la detección de cierta información como: la anatomía radicular, la presencia de alteraciones alrededor de las raíces, la pérdida ósea, los diferentes tipos de reabsorciones radiculares, las fracturas radiculares y otros aspectos importantes en la planificación de una cirugía apical. A través de la imágenes obtenidas a partir de la tomografía computarizada de haz cónico (TCHC), en inglés llamada cone-beam computed tomography (CBCT), se puede obtener una mayor información diagnóstica en comparación a las RP preoperatorias; información que influye directamente en el plan de tratamiento del clínico, especialmente en los casos de dificultad alta. Por todo a ello, en este artículo se presentan diferentes situaciones clínicas en las que la CBCT juega un papel fundamental en relación al plan de tratamiento endodóncico


No disponible


Assuntos
Humanos , Dente não Vital/diagnóstico por imagem , Dente não Vital/terapia , Tomografia Computadorizada de Feixe Cônico/métodos , Abscesso Periapical/diagnóstico por imagem , Reabsorção Óssea/diagnóstico por imagem , Reabsorção de Dente/diagnóstico por imagem , Traumatismos Dentários/diagnóstico por imagem , Doenças Periapicais/diagnóstico por imagem , Tecido Periapical/diagnóstico por imagem
13.
Endodoncia (Madr.) ; 36(3): 44-50, dic. 2018. ilus
Artigo em Espanhol | IBECS | ID: ibc-178385

RESUMO

Introducción: La metamorfosis cálcica se presenta comúnmente tras lesiones traumáticas y se caracteriza por presentar depósitos de tejido duro dentro del espacio pulpar, obliterando parcial o totalmente la cámara pulpar y/o el conducto radicular. Este proceso suele provocar un cambio de coloración de la corona clínica haciéndola más oscura y opaca. Caso clínico: Paciente mujer de 40 años acude a la consulta motivada por una preocupación estética debido al oscurecimiento del diente 21. Se proponen varias opciones de tratamiento, hasta que finalmente se opta por el tratamiento de conductos de forma ortógrada, así como blanqueamiento interno del diente. Conclusión: El plan de tratamiento en dientes con metamorfosis cálcica sin patología periapical y con compromiso estético partirá siempre desde el más conservador. Es esencial en el tratamiento de estos dientes la experiencia del operador, así como el buen manejo del microscopio y los ultrasonidos, herramientas fundamentales para su abordaje


Introduction: Calcium metamorphosis commonly occurs after traumatic injuries and is characterized by hard tissue deposits within the pulp space, partially or totally obliterating the pulp chamber and/or the root canal. This process usually causes a change in the color of the clinical crown, making it darker and more opaque. Clinical case: A 40-year-old female patient came to the clinic motivated by an aesthetic concern due to the darkening of the tooth 21. Various treatment options are proposed, until finally the endodontic treatment is chosen, as well as internal bleaching of the tooth. Conclusion: The treatment in teeth with calcium metamorphosis, without periapical pathology and with aesthetic compromise, should always be the most conservative. It is essential in the treatment of these teeth the experience of the operator, as well as the correct use of the microscope and ultrasounds, which are fundamental tools for its approach


Assuntos
Humanos , Feminino , Adulto , Clareamento Dental/métodos , Dente não Vital/terapia , Depósitos Dentários/terapia , Traumatismos Dentários/diagnóstico por imagem , Traumatismos Dentários/terapia , Espectrometria de Fluorescência/métodos , Cavidade Pulpar/diagnóstico por imagem , Tecido Periapical/diagnóstico por imagem
14.
Cell Physiol Biochem ; 49(3): 884-898, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-30184545

RESUMO

BACKGROUND/AIMS: Periapical periodontitis is caused by bacterial infection and results in both one destruction and tooth loss. Osteopontin (OPN) is a secreted phosphorylated glycoprotein that participates in bone metabolism. METHODS: Thirty-three patients with chronic periapical periodontitis and 10 patients who had undergone the orthodontic removal of healthy tooth tissue (control) at the periodontal ligament were investigated, and an animal model of mouse periapical periodontitis was established for an in vivo analysis. The relationship between OPN and bone destruction during periapical periodontitis was analyzed. Osteoblasts and osteoclasts were cultured in vitro and treated with lipopolysaccharide. An inhibitor of NF-κB was used to pretreat the transfected cells. RESULTS: OPN increased osteoclast proliferation and differentiation, but reduced osteoblasts proliferation and differentiation. OPN activated the NF-κB pathway during periapical periodontitis and accelerated the transfer and phosphorylation of P65 from the cytoplasm to the nucleus. CONCLUSION: This study demonstrated that OPN played important roles in the progression of periapical periodontitis, and a dual role in bone metabolism during periapical periodontitis, linking osteoclasts and osteoblasts. The underlying mechanism may be related to the NF-κB pathway.


Assuntos
NF-kappa B/metabolismo , Osteopontina/metabolismo , Periodontite Periapical/patologia , Transdução de Sinais , Animais , Catepsina K/genética , Catepsina K/metabolismo , Diferenciação Celular/efeitos dos fármacos , Modelos Animais de Doenças , Humanos , Interleucina-6/genética , Interleucina-6/metabolismo , Lipopolissacarídeos/farmacologia , Masculino , Mandíbula/diagnóstico por imagem , Camundongos , Camundongos Endogâmicos C57BL , Osteopontina/antagonistas & inibidores , Osteopontina/genética , Periodontite Periapical/diagnóstico por imagem , Periodontite Periapical/metabolismo , Tecido Periapical/diagnóstico por imagem , Tecido Periapical/metabolismo , Ligamento Periodontal/metabolismo , Células RAW 264.7 , Interferência de RNA , RNA Interferente Pequeno/metabolismo
16.
Int Endod J ; 51(11): 1261-1270, 2018 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-29737545

RESUMO

AIM: To evaluate the influence of different apical enlargement protocols on the radiographic and histological healing of apical periodontitis in rats. METHODOLOGY: Apical periodontitis was induced bilaterally in the mandibular right and left first molars of 24 Wistar rats by pulp exposure to the oral cavity for 3 weeks. A standard serial root canal preparation technique was performed in the molar of one side, whilst the opposite side was the control group. Rats were randomly divided into three experimental groups (n = 8), according to the diameter of apical enlargement during root canal preparation: K-files size 20 (EG1), size 25 (EG2) and size 30 (EG3). Each animal was its own positive control, because the opposite arch remained untreated. Root canals were filled with a standard technique. After 3 weeks, the animals were euthanized. The main outcome of apical periodontitis healing was evaluated radiographically (mm2 ) and histologically (ordinal scores of inflammation) using a HE staining technique. The measurement of effect was obtained between the three experimental groups by carrying out generalized estimating equations, with Poisson regression with robust variance, pairing each experimental group with its respective control group within animals, adjusted for the mean within animal differences, with α = 5%. RESULTS: The mean and standard deviations of radiographic apical periodontitis size (mm2 ) and intensity of histological inflammatory scores were, respectively: EG1 (0.44 ± 0.27; 2.25 ± 0.46), EG2 (0.33 ± 0.10; 2.50 ± 0.53) and EG3 (0.22 ± 0.08; 2.63 ± 0.74). After 3 weeks, a significantly more favourable radiographic repair was observed when larger apical enlargement was performed (EG3), compared to EG1 and EG2 (P = 0.001). All experimental groups were associated with a significant difference on the radiographic and histological healing of apical periodontitis compared with its respective control group. CONCLUSION: Under the experimental conditions of this study, a larger apical enlargement protocol favoured a more rapid radiographic repair of apical periodontitis in rats after a 3-week follow-up.


Assuntos
Periodontite Periapical/patologia , Periodontite Periapical/terapia , Tecido Periapical/patologia , Ápice Dentário/patologia , Animais , Reabsorção Óssea/diagnóstico por imagem , Reabsorção Óssea/patologia , Cavidade Pulpar/patologia , Feminino , Inflamação , Mandíbula , Dente Molar , Periodontite Periapical/diagnóstico por imagem , Tecido Periapical/diagnóstico por imagem , Ratos , Ratos Wistar , Materiais Restauradores do Canal Radicular , Preparo de Canal Radicular/instrumentação , Preparo de Canal Radicular/métodos , Tratamento do Canal Radicular/métodos , Ápice Dentário/diagnóstico por imagem , Cicatrização/fisiologia
17.
Int Endod J ; 51(10): 1069-1076, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-29603299

RESUMO

AIM: To evaluate postoperative pain and radiographic evidence of periapical healing in teeth with apical periodontitis treated in one visit with an additional final irrigation using 2% chlorhexidine (CHX) and to compare the results with conventional two-visit root canal treatment (RCT) with an intracanal calcium hydroxide (CH) dressing as a control group. METHODOLOGY: Ninety asymptomatic maxillary anterior teeth with periapical lesions were treated by a single operator. Root canals were prepared using the step-back technique with manual instrumentation with 2.5% NaOCl and 5% EDTA as irrigants. Half of the teeth were randomly assigned to the one-visit (OV) group and received an additional final rinse with 2% CHX before canal filling. The other teeth were treated in two visits (TV) with a CH paste made by mixing CH powder and distilled water as an interappointment dressing. All patients were recalled and investigated clinically and radiographically for 24 months. Postoperative pain at 24-48 h and changes in apical bone density indicating radiographic healing were evaluated statistically using the Mann-Whitney U-test followed by the Friedman and the Wilcoxon tests (α = 0.05). RESULTS: There were no significant differences between two groups regarding the incidence of postoperative pain at 24 h (OV group 50% no pain, 47.6% mild, 2.4% moderate pain/TV group 55% no pain, 42.5% mild, 2.5% moderate pain) and at 48 h (OV group 95% no pain, 5% mild pain/TV group 98% no pain, 2% mild pain). None of the patients reported severe postoperative pain, swelling and/or flare-ups during the follow-up period. There was no significant difference in the radiographic healing rates (OV group 97.6% PAI 1 and/or PAI 2 and 2.4% PAI 3/TV group 95% PAI 1 and/or PAI 2 and 5% PAI 3; P > 0.05). CONCLUSION: Both groups provided favourable and similar postoperative pain and periapical healing rates at 24 months. Thus, one-visit RCT with a final rinse with 2% CHX is an acceptable alternative to two-visit RCT with CH as temporary dressing in maxillary anterior teeth.


Assuntos
Clorexidina/uso terapêutico , Dor Pós-Operatória/epidemiologia , Periodontite Periapical/tratamento farmacológico , Irrigantes do Canal Radicular/uso terapêutico , Tratamento do Canal Radicular/métodos , Adulto , Feminino , Humanos , Incidência , Masculino , Medição da Dor , Periodontite Periapical/diagnóstico por imagem , Tecido Periapical/diagnóstico por imagem , Estudos Prospectivos , Radiografia Dentária , Materiais Restauradores do Canal Radicular , Obturação do Canal Radicular , Irrigação Terapêutica
18.
J Endod ; 44(5): 722-727, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29551205

RESUMO

INTRODUCTION: The visual search patterns of dentists and the areas that attract their attention when interpreting dental periapical radiographs are currently unknown. This research identifies areas and patterns of visual fixation when observing dental periapical radiographs. METHODS: In an observational study using eye tracking technology and a convenience sample of 44 observers, the interpretations of 4 dental periapical radiographs were recorded using Camtasia Software (TechSmith, Okemos, MI) with a gaze tracking "bubble" denoting where within the radiograph the observers' eyes gazed. The recorded observations included the scanning pattern, the area of first fixation, and revisits of areas. Also noted was whether the area of first fixation or revisit was radiopaque, radiolucent, or of normal radiodensity and whether it was a coronal or radicular area. RESULTS: The first fixation is more likely to be an area of high contrast that is either radiopaque or radiolucent compared with areas that were normal or of average gray scale. Significantly more revisits occurred on areas that were radiopaque and located in the radicular area. Of the 4 categorized scanning patterns, tooth by tooth scanning predominated. CONCLUSIONS: When interpreting dental periapical radiographs, significantly more observers initially fixated on areas of the radiograph that were of high contrast (ie, radiopaque or radiolucent) compared with "normal areas." A tooth by tooth scanning pattern was most commonly used.


Assuntos
Odontólogos/psicologia , Movimentos Oculares , Fixação Ocular , Doenças Periapicais/diagnóstico por imagem , Tecido Periapical/diagnóstico por imagem , Radiografia Dentária , Odontólogos/estatística & dados numéricos , Medições dos Movimentos Oculares , Humanos , Reconhecimento Visual de Modelos , Projetos Piloto , Radiografia Dentária/métodos , Radiografia Dentária/psicologia
19.
Belo Horizonte; s.n; 2018. 28 p. ilus, tab, graf.
Tese em Inglês, Português | BBO - Odontologia | ID: biblio-986906

RESUMO

As reabsorções radiculares externas progressivas inflamatórias (RREI) e por substituição (RRES) representam a sequela mais frequente em dentes permanentes reimplantados ou que sofreram luxações intrusivas. O exame clínico, incluindo os sinais e sintomas e ainda os exames complementares, em destaque os exames radiográficos são fatores determinantes para o diagnóstico. A radiografia periapical (RP) é o exame complementar de escolha para o acompanhamento em casos de RRE, no entanto, as imagens bidimensionais apresentam sobreposições de estruturas anatômicas. Para suprir as limitações apresentadas pelas radiografias convencionais as imagens multiplanares vêm sendo amplamente utilizadas, destacando-se a tomografia computadorizada de feixe cônico. O objetivo do presente estudo foi fazer uma avaliação do desempenho de exames de imagem da TCFC e de radiografias periapicais para diagnóstico dos diferentes tipos de RRE pós-traumáticas, em diferentes estágios. A amostra foi composta por 29 pacientes, com 39 incisivos superiores reimplantados após avulsão. Radiografias periapicais e TCFC realizadas no mesmo dia foram examinadas de forma independente por 2 avaliadores, a fim de identificar a presença, o tipo e a extensão da reabsorção radicular nos dois exames. As reabsorções leves e as inflamatórias foram mais frequentemente identificadas pela TCFC enquanto as reabsorções moderadas a severas e por substituição nas radiografias periapicais. Pode-se concluir que apenas uma técnica radiográfica não é suficiente para o diagnóstico de todos os tipos e gravidade de RRE, sendo assim a TCFC é importante para complementar o exame periapical, principalmente em estágios iniciais.


The progressive external inflammatory root resorptions (IERR) and substitution (RERR) represent the most frequent sequelae in permanent teeth replanted or that suffered intrusive dislocations. The clinical examination, including the signs and symptoms and the complementary exams, highlighting the radiographic examinations are determining factors for the diagnosis. Periapical radiography (PR) is the complementary exam of choice for follow-up in RRE cases, however, two-dimensional images show overlaps of anatomical structures. In order to overcome the limitations presented by conventional radiographs, multiplanar images have been widely used, particularly concomitant computed tomography. The objective of the present study was to make a evaluation of the performance of CBCT and periapical radiographs for the diagnosis of different types of posttraumatic RRE at different stages. The sample consisted of 29 patients, with 39 superior incisors reimplanted after avulsion. Periapical radiographs and CBCT performed on the same day were independently examined by 2 evaluators in order to identify the presence, type and extent of root resorption in both examinations. Mild and inflammatory resorptions were more frequently identified by CBCT while moderate to severe resorptions and by replacement in periapical radiographs. It can be concluded that only one radiographic technique is not sufficient for the diagnosis of all types and severity of RER, so CBCT is important to complement periapical examination, especially in the early stages.


Assuntos
Humanos , Masculino , Feminino , Tecido Periapical/diagnóstico por imagem , Reabsorção da Raiz , Reimplante Dentário , Diagnóstico por Imagem , Radiografia Dentária Digital , Tomografia Computadorizada de Feixe Cônico , Radiologia
20.
ScientificWorldJournal ; 2017: 2427060, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29270461

RESUMO

AIM: To compare digital images of conventional radiographs with the original radiographs for perceived clarity of periapical lesions and the quality of root canal treatment. MATERIALS AND METHODS: One hundred and four intraoral periapical radiographs of patients with endodontically treated teeth were randomly selected. The radiographs were digitized using an MD300 USB X-ray Reader. The digital images were transferred to an HP laptop. Three evaluators compared each conventional radiograph with the matching digital image. The images were ranked for clarity and assessed for diagnostic quality; data were analyzed using the Reliability Calculation "ReCal." Results. Both the digital images and conventional films had comparable clarity and diagnostic quality. Results indicated a moderate agreement between the evaluators. CONCLUSIONS: Conventional radiographs digitized using an MD300 USB X-ray Reader have similar clarity and diagnostic quality in comparison to the original radiographs.


Assuntos
Cavidade Pulpar/diagnóstico por imagem , Tecido Periapical/diagnóstico por imagem , Intensificação de Imagem Radiográfica/métodos , Radiografia Dentária/métodos , Humanos , Intensificação de Imagem Radiográfica/instrumentação , Intensificação de Imagem Radiográfica/normas , Radiografia Dentária/instrumentação , Radiografia Dentária/normas , Tratamento do Canal Radicular/normas
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